JOURNAL DE NEUROCHIRURGIE
Volume 16, Numéro 1, Pages 14-18

Intracranial Germ Cell Tumors,the Experience Of The Algiers University Hospital And A Literature Review .

Authors : .daou Djida . Felissi Yacine . Morsli A.halim .

Abstract

PURPOSE: Primary intracranial germinomas (PIGs) are rare malignant brain tumors that represent approximately 0.2% to 1.7% of all primary intracranial tumors. In this study, clinical outcomes of thirteen consecutive PIGs have been presented in hospital university of Algiers and a literature review. MATERIAL and METHODS Thirteen patients were treated from 1999 to 2020 for histologically verified primary intracranial germinoma. Median age was 22 years (range:17 months–42 years). Most of patients were males and received only radiotherapy after surgery. RESULTS: seven patients were in complete remission, three of them died by surgical and endocrine complications, one patient had recurrence two years after complete remission .one patient died after radiotherapy . CONCLUSION: PIG is a mostly malignant tumors. They are radiosensitive tumors. Subtotal or near-total resection using stereotactic guide or direct surgery to confirm the histopathological diagnosis followed by chemotherapy and radiotherapy rather than GTR is therefore the treatment of choice.

Keywords

: Primary intracranial germinoma, Pineal gland, Suprasellar region, Radiotherapy, Drop metastasis.