Nutrition & Santé
Volume 10, Numéro 1, Pages 62-71

Phytochemical Components And Antioxidant And Antimicrobial Activities Of Essential Oils From Native Tunisian Thymus Capitatus And Rosmarinus Officinalis

Authors : Ben Jemaa Mariem . Snoussi Majdi . Falleh Hanene . Serairi Beji Raja . Ksouri Riadh .


This study aimed on the phytochemical prospection of Thymus capitatus and Rosmainus officinalis essential oils and their oral toxicity evaluation. Chemical analysis of tested essential oils was carried out using gas chromatography combined to mass spectroscopic. Their safety limit was evaluated by acute toxicity. The antioxidant activity was estimated using in vitro methods. The antimicrobial activity was evaluated against twelve pathogenic germs. Obtained results showed that carvacrol and 1,8-cineol were the major compounds of Thymus capitatus and Rosmarinus officinalis essential oils. Acute toxicity results exhibited that both tested essential oils were inoffensive at 2000 mg/kg. Additionally, Thymus capitatus essential oil presented higher antioxidant activity than Rosmarinus officinalis: DPPH assay results showed lower IC50 for Thymus capitatus essential oil than Rosmarinus officinalis. Concerning the antimicrobial results, Thymus capitatus essential oil presented greater efficacy than R. officinalis. Overall, Thymus capitatus and Rosmarinus officinalis essential oils have strong potential applicability for pharmaceutical industries.


Acute toxicity ; Biological Activities ; Essential Oils ; GC-MS ; Rosmarinus officinalis ; Thymus capitatus