Materials & biomaterials science
Volume 3, Numéro 2, Pages 065-070
2020-06-01
Effect Of Acidification On Biological Proprieties Of Sodium Carboxymethylcellulose
Authors : Mansouri Lamia . Elkolli Meriem . Zohra Bouanane .
Abstract
Sodium carboxymethyl cellulose is frequently used in medicine for its excellent biological properties. In addition, it is known that the polymer chain modification can lead to the change or improvement of its biological properties, for this reason Sodium Carboxymethyl cellulose (NaCMC) was subjected to an acidification reaction by hydrochloric acid. Characterization and identification of acidified carboxymethylcellulose (HCMC) was made by Fourier transformed Infrared spectroscopy (FT-IR), Elemental analysis (XRF) and Ther- mal analysis (TGA - DSC). The opacity measurement shows a marked difference in pow- ders structure. The blood-clotting tests demonstrate that HCMC is more hemostatic than NaCMC. Mucoadhesion exhibits a pronounced increase in adhesion times of HCMC contra- ry to NaCMC on the gastric and intestinal mucosa. Besides, biodegradability is established.
Keywords
Carboxymethylcellulose, Acidification, Blood clotting, Mucoadhesion, Biodegradability
Les articles similaires
Bouchal Fatiha
.
Ayachi Nabila
.
Benmeziane Rosa
.
Lahlou Soraya
.
pages 5-10.
Hadj Sadok T.
.
Chaouch F.z.
.
Boutekrabt A.
.
pages 85-96.
Ferfera-harrar H.
.
Aiouaz N.
.
Dairi N.
.
pages 80-85.
Benhalima T.
.
Lerari D.
.
Ferfera-harrar Hafida
.
pages 61-66.
Diaf M.
.
Khiari S.
.
Labbaci K.
.
Guerbous L.
.
Jouart J. P.
.
pages 25-31.
