JOURNAL DE NEUROCHIRURGIE
Volume 15, Numéro 2, Pages 05-14
2020-09-19
Epilepsy Surgery In Pediatric Population: Surgical Results And Predicors Of Outcome
Authors : Handis Chafik . Tanrikulu Bahattin . özek M. Memet .
Abstract
Introduction : Drug-resistant epilepsy in children is a common pathology, having deleterious effects on cognitive and learning functions. After attempting different antiepileptic medication (AED) for treatment, surgery is indicated in patients with a refractory profile. Our objective is to report different statistical parameters of our patients, results of surgical techniques and define some predictors of outcome. Methods: We reviewed retrospectively 96 pediatric patients operated in our institution between 2005 and 2019, and analyzed several demographics and epilepsy parameters in order to define prognostic factors.Surgical techniques, histopathology of lesions were also included in our investigation. Results: The study population was composed of 96 patients; 63 male (65.6℅),33 female(34.4℅). Median age at seizure onset was 2 years (range: 1 day-15years). Median age at surgery was 7.3 years (range:3 months-18 years). Mean duration of seizures was 4.3 years (range:10 days-17 years). Median follow up was 4.9 years (range:4 months-13.7 years). The best results regarding seizures were obtained in resective surgery group. The age of epilepsy onset was the important prognostic factor of outcome. Conclusion: Surgery is an effective therapeutic modality for refractory epilepsy in children, without mortality and/or a significant morbidity. Earlier onset of seizures is one of the bad prognosis factors that must be considered before surgical procedures.
Keywords
Refractory epilepsy ; drug resistant ; surgery
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