Applied Biology in Saharan Areas
Volume 2, Numéro 2, Pages 1-9

Evaluation Of Antioxidant And Antimicrobial Activity Of Polyphenol And Encapsulated Polyphenol From The Seeds Of Melia Azedarach

Authors : Ben Yacoub Assia . Ouladsmane2 Mohamed . Boutemak Kalida . Hadj-ziane Zafour1 Amel .


Abstract – Melia azedarach contains several phytochemical compounds such as phenols, flavonoids, alkaloids, tannins, glycosides, steroids, saponins and terpenoids. Melia azedarach has attracted a lot of attention from researchers as one of the most versatile herbal medicines, having a wide range of biological activities, including anticancer, antimalarial, analgesic, anti-inflammatory, diuretic, astringent and gastric. Polyphenol from the seeds of Melia azedarach showed antibacterial activity against the bacteria tested (Escherichia coli and Pseudomonas aeruginosa) at all concentrations. For the encapsulated polyphenol from the seeds of Melia azedarach, we observed a decrease in the inhibitory effect for the bacteria tested. The biological study for the evaluation of the antioxidant activity of polyphenol and encapsulated polyphenol was evaluated by the DPPH method. The inhibition of the DPPH radicals of polyphenol from the seeds of Melia azedarach and of encapsulated polyphenol from the seeds of Melia azedarach was 85.58±0.5 % and 49.52 ±0.6 % respectively. Key words:


Antioxidant activity, antimicrobial activity, polyphenol, encapsulated polyphenol, seeds of Melia azedarach.