Algerian Journal of Materials Chemistry
Volume 2, Numéro 1, Pages 20-32
2019-04-08

Preparation Of Biopolymer/cuo-magadiite Biocomposite Beads By Chemical Reduction Method And Their Antibacterial Activity



Authors : Mokhtar Adel . Abdelkrim Soumia . Djelad Amal . Bengueddach Abdelkader . Sassi Mohamed .

Abstract

In this work, an inorganic-organic nanocomposite material was prepared by combining copper exchanged-magadiite (Cu-magadiite) material with chitosan. The synthesis was carried out by direct dispersion of the Cu-magadiite in the chitosan matrix. The mixture obtained is shaped into beads with an average diameter of about 1~1.2 mm. These beads were then contacted with a solution of NaBH4 in ethanol in order to reduce loaded copper ions into copper nanoparticles species. The resulting nanocomposite material, named Cu-NPs-magadiite/chitosan, was characterized by X-ray diffraction (XRD), Fourier transforms infrared spectroscopy (FTIR), scanning electron microscopy (SEM), Thermogravimetric (TG), UV-Visible diffuse reflectance (UV-Visible DR) and EDX analysis. The results show that the layered silicate magadiite was completely exfoliated confirming the formation of the organic-inorganic composite material. Indeed, the encapsulation of the layered silicate was confirmed by the SEM images, which is presented as micron free aggregates included in the cavities of a continuous polysaccharide matrix. Otherwise, they confirm also the formation of copper nanoparticles (CuNPs) which are probably immobilized inside the magadiite-chitosan solid matrix. The antibacterial activity against Escherichia coli and Staphylococcus aureus of the nanocomposite was highlighted by the disc inhibition method and the minimum inhibitory concentration (MIC) was determined. The CuNPs-magadiite/chitosan nanocomposite material showed a very efficient bactericidal effect against both pathogen E. Coli and staphylococcus bacteria strains. Additionally, the MIC values obtained for nanocomposite are of 0.25 μg/L against S. aureus and of 0.50 µg/L against E. coli. Therefore, encapsulation of low levels of magadiite as a carrier for copper ions in the chitosan matrix has proven to be a good method for developing functional composites that can potentially be applied as antibacterial agents against pathogen gram+ and gram- bacterial strains.

Keywords

Chitosan-magadiite-nanocomposite beads-NaBH4-antibacterial activity.

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