Photodegradation study of amlodipine by the synthetic TiO2-SiO2

Souhila, Rabhi; Hayet, Belkacemi; Salima, Chebbi; Leila, Ait Brahem

Algerian Journal of Engineering Research
Volume 1, Numéro 1, Pages 48-53
2017-06-01

Photodegradation Study Of Amlodipine By The Synthetic Tio2-sio2

Authors : Souhila Rabhi . Hayet Belkacemi . Salima Chebbi . Leila Ait Brahem .

Abstract

In this work, we aim to develop a catalyst TiO2 doped with SiO2, varying their mass percentages, synthesized thermally in the presence of Na2CO3 used as cooking fondant. The doping was carried out at sintering temperatures of 800 °C, 900 °C and 1000 °C. The synthesized catalysts were characterized by different spectroscopic techniques and were then applied for the photodegradation of amlodipine by exposure to Ultra Violet rays (250 nm-265 nm). The mass of the catalyst, the time of photodegradation and the concentration of amlodipine were optimized. The photodegradation kinetics of amlodipine was monitored by UV-visible spectroscopy. The best photodegradation was obtained at a concentration of 70 m /L of amlodipine and for a time of 15 min of UV exposure. Structural analyzes by FTIR, TGA/TDA, and morphological by SEM have revealed new phases (anatase, brookite) in the materials.