Agriculture
Volume 3, Numéro 1, Pages 30-36
2012-06-30

Toxicite Aigue De L'huile De Ricinus Communis Chez Les Souris Blanches Femelles Mus Musculus

Auteurs : Guergour H . Mahdeb N . Allouni R . Benouadah Z . Bouzidi A .

Résumé

The acute toxicity of the crude extract oil from Ricinus communis L was assessed by determining the (LD 50) female mice Mus Musculus who received different doses of the oil by intraperitoneal administration and the study of some parameters related particularly liver and kidney. This study allowed to calculate the LD 50 = 5623.41 mg / kg, with a significant decrease in the relative mass of the heart, liver and brain after the first day, and lung, heart, kidney and brain after the fifth day. Biochemical analyzes revealed a significant increase of creatinine after the fifth day, and an increase in ALP and GOT after 1 day while glucose showed no significant change. The histological study of the liver shows the attack by the péliose and the congestions of the renal tubules on the level of kidneys of the mice treated with the castor oil especially after the 5th day of the application. The whole of the biochemical and histological parameters shows the delayed toxic effect of the castor oil (after several days of its application).

Mots clés

Ricinus communis, castor oil, toxicity, liver, kidney

Effect Of Administration Of Ginseng Solution Panax Ginseng On Blood Coagulation Parameters Among A Population Of Mice (mus Musculus)

Aissiou Mohammed Yehya El Amin .  Berhoun Celina .  Benfardjellah Amira Ghizlaine .  Bekka Selma . 
pages 2810-2818.


Insecticidal Activity Of Algerian Castor Extracts Ricinus Communis Against The Green Rose Aphid Macrosiphum Rosae

El Haddad Djillali .  Toubal Souheyla .  Bouchenak Ouahiba .  Boumaza Sarah .  Merah Maroua .  Yahiaoui Karima .  Arab Karim . 
pages 2827-2833.