PhytoChem & BioSub Journal
Volume 7, Numéro 3, Pages 95-102
2013-11-25

Synthesis Of 2 (1,2,3)-triazolines Via 1,3-dipolar Cycloaddition Between Organic Azides And 1-morpholinocyclopentene Derivatives

Authors : Ouasti Fatima-zahra . Hamadouche Mohammed . El Abed Douniazad .

Abstract

The synthesis of some bicyclic 2-1,2,3-triazolines performed by 1,3-dipolar cycloaddition reaction between cyclopentenic enamines and arylazides, at room temperature in ether, led to the expected triazolines with yields which vary according to the structure of the arylazide and enamine. The structure of the obtained triazolines was determined by the usual spectroscopic methods: (IR, 1H NMR, 13C NMR).

Keywords

1,3-dipolar cycloaddition, 1-morpholinocyclopentene, Organic azides, Triazolines Secondary amine, Heterocycles, Biological activities