PhytoChem & BioSub Journal
Volume 8, Numéro 2, Pages 60-69
2014-07-05
Antioxidant And Cytotoxic Activities Of Three Different Fractions Of Lonicera Quinquelocularis (translucent Honeysuckle) Plant
Authors : Khan Muhammad Imran . Khan Dilfaraz . Ahmed Mushtaq . Khan Shafiullah . Khan Rahmat Ali . Mushtaq Nadia . Noor Shah .
Abstract
The cytotoxic and antioxidant activities of a plant count for its effectiveness against various lethal and sever diseases such as cancer, Parkinson Alzheimer and Diabetics etc. Free radicals in the form of reactive oxygen species and reactive nitrogen species may be the main cause of these severe health issues. Medicinal plants with antioxidant and cytotoxic properties have been proved to be the most reliable method of treatment of the mentioned diseases. In the present study antioxidant and cytotoxic potential of three different fractions i.e. ethanol, chloroform and ethyl acetate extracted from Lonicera quinquelocularis (Translucent Honeysuckle) plant were tested. The ethanolic and ethyl acetate fraction showed highest scavenging ability than chloroform fraction against DPPH and ABTS free radicals. In cytotoxic assays, chloroform fraction showed highest lethal effects than ethanolic and ethyl acetate fraction. The data obtained from the experimental work revealed that all the three fractions isolated from Lonicera quinquelocularis (Translucent Honeysuckle) possess antioxidant and cytotoxic properties.
Keywords
Free radicals, anticancer agents, cytotoxic, phytochemicals, antioxidant
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