Algerian Journal of Natural Products
Volume 3, Numéro 3, Pages 177-184
2015-07-25
Effects Of Maternal Linseed Oil Supplementation On Oxidative Stress Markers In Cafeteria Diet Induced Obese Rats
Authors : Merzouk Hafida . Benaissa Nawel . Merzouk Sid Ahmed . Narce Michel .
Abstract
We investigated the role of dietary linseed oil in the modulation of biochemical parameters and oxidant/antioxidant markers in cafeteria-induced obese rats and their offspring. Female wistar rats were fed on control or cafeteria diet, supplemented or not with linseed oil (5%) for one month before and during the gestation. At parturition, the mothers and their offspring were killed. Weight gain, food intake, serum biochemical and oxidant/antioxidant markers were determined. Cafeteria diet induced a significant increase in body weight, food intake and adverse alterations in biochemical parameters such as an increase in serum glucose, triglyceride, cholesterol and oxidant markers. Linseed oil supplementation induced a reduction in weight gain, serum lipids and a modulation of oxidative stress, improving metabolic status. In conclusions, linseed oil displayed remarkable health benefits by decreasing plasma and oxidant/antioxidant markers in both obese mothers and their newborns.
Keywords
cafeteria; linseed oil; maternal obesity; lipid metabolism; newborn;
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