Algerian Journal of Natural Products
Volume 3, Numéro 2, Pages 153-158
2015-03-08
In Vitro Anti-arthritic Activity Of Tecoma Stans (linn.) Leaves
Authors : Prajapati, Dharmeshkumar . Patel N. M. .
Abstract
The World Health Organization (WHO) estimates 80% of the world population presently use herbal medicine for some aspects of primary health care. Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disorder that may affect many tissues and organs, but principally attacks synovial joints. There are many herbs which are described in Ayurveda for arthritis. The medicinal plant contains flavonoids, terpenes, quinones, catechins, alkaloids, anthocyanins and anthoxanthins phytoconstituents, having anti-inflammatory effects. Tecoma stans (Linn.) belongs to the family of Bignoniaceae. The root of Tecoma stans as diuretic, vermifuge and tonic. Pharmacological reports revealed that it is having antidiabetic, anticancer, antioxidant, anti-inflammatory activity, antimicrobial, and antifungal properties, and extensively used in the treatment of diabetes. Alcohol, Water, successive extracts of Petroleum ether, Chloroform, Methanol and Water extracts of T. stans leaves were tested for Antiarthritic activity using Diclofenac sodium as standard by In-vitro models like, Inhibition of protein denaturation and effect on membrane stabilization. Alcohol, Water and succesive Methanol extracts of T. stans leaves exhibited significant Antiarthritic activity. The results of the investigations justify us the folklore use of T. stans leaves in the treatment of inflammation during arthritis and the plant is worth for further chemical isolation and pharmacological investigations.
Keywords
T. stans, Antiarthritic activity, Bignoniaceae
Les articles similaires
Laouini S. E.
.
Segni L.
.
Gherraf N.
.
Ouahrani M. R.
.
Mokni S.
.
pages 171-182.
Patel Sohankumar Anilbhai
.
Rajendra S. V.
.
Ramchandra Setty S.
.
pages 233-240.
Boudebaz Khadidja
.
Nia Samira
.
Trabelsi Ayadi Malika
.
Cherif Jamila Kalthoum
.
pages 146-152.
Prajapati Dharmeshkumar
.
Patel Sohan A.
.
pages 159-163.
Zellagui Amar
.
Boutellaa Saber
.
Arab Yasmine
.
Gherraf Noureddine
.
pages 155-160.
