Journal of New Technology and Materials
Volume 7, Numéro 2, Pages 113-116
2017-12-30
Synthesis,, Spectral Studies And Antimicrobial Activity Of A New Hexahydrotriazine Compound
Authors : Malki Souhila . Mazouz Wissam . Frank Schaper . Bouchemma Ahcen . Bouhenguel Mustapha . Hadjem Meriem . Valérie Hardouin Duparc . Lefrada Leila .
Abstract
An unsymmetrical original structure of 1.3- bis( 2-bromophenyl)-5-isopropyl-1.3.5-Triazacyclohexane was synthesized via a long one-step mixed condensation reaction of 2:1stoichiometric ratio, 2-bromoaniline and isopropylamine with formalin. The desired novel compoundwas obtained as colorless needles in good yield of 71%. The Characterization of the synthesized compound has been done by different spectroscopic methods like FT-IR, 1H NMR ,13C NMR, UV , and elementary analysis. In this researchwork,we tested the antimicrobial activity of this new product where we used Gram‐positive and Gram‐negative bacteria by the diffusion method on agar medium.
Keywords
synthesis; amine; Hexahydrotriazines; antimicrobial activity; spectral techniques.
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