Journal of Molecular and Pharmaceutical Sciences
Volume 2, Numéro 2, Pages 59-109
2024-07-25
Phytochemicals As Antimicrobial Potentiators: A Review
Authors : Belattar Nadjah . Barhouchi Badra . Benayache Sara . Merabet Souad .
Abstract
In the last few decades, ethnopharmacology research has focused on finding novel anti-infection agents. The antimicrobial activity of plant extracts used in traditional medicine, essential oils, or isolated compounds such as alkaloids, flavonoids, terpenes, coumarins, quinones, etc., among others, is the subject of much research. Some of these compounds were procured through bio-guided isolation after the identification of plant antimicrobial activity. Particular research focuses on the natural flora of a specific region or country and the ability of a plant or principle to combat a concrete pathological microorganism. The investigation of plant extracts, essential oils, and their isolated compounds for their antimicrobial properties requires the establishment of some general considerations. The definition of common parameters, such as plant material, techniques used, growth medium, and microorganisms tested, is extremely important. This report describes the principal groups of phytochemicals, as well as the evaluation of their therapeutic potential to guide pharmacological research. It allows us to inventory the frequency of use of medicinal plants containing active substances of curative interest, so this work aimed to elaborate an exhaustive list of bioactive compounds and find a correlation between their quantification and their antimicrobial capacity.
Keywords
Antimicrobials ; Phenolic compounds ; Quinones ; Flavonoids ; Tannins ; Coumarins ; Terpenoids and essential oils ; Alkaloids
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