Applied Biology in Saharan Areas
Volume 3, Numéro 3, Pages 44-207

Antinociceptive And Anti-inflammatory, Anti-oxidant Activities Of Launaea Nudicaulis Aquous Extract In Experimental Animals

Authors : Seddiki Lamia Salima .

Abstract

Antinociceptive and anti-inflammatory potentials of aqueous extract of Launaeanudicaulis (LNAE) were evaluated against mice. Antinociceptive effects of LNAE were assessed in mice using the acetic acid-induced writhing and formalin test. Anti-inflammatory effectsof LNAE in three different doses, namely, 30, 100, and 300 mg/kg, were evaluated by utilizing mice representing various changes associated with inflammation, namely, histamine and serotonin-induced paw oedema, formalin-induced paw oedema, acetic acid-induced vascular permeability. Also LNAE was antioxidant activities evaluated using DPPH and TPC.The extract showed statistical significant inhibition of induced nociception and inflammation in dose dependent manner. The dose of extract 100 mg/kg significantly inhibited pain and inflammation against control (p< 0.001). The present study scientifically demonstrated the antinociceptive and anti-inflammatory potential of LNAE. These effects may be attributed to the presence of polyphenolic phytoconstituents in the extract. Keywords:Launaeanudicaulis ;Antinociceptive ; anti-inflammatory ; antioxidant activity.

Keywords

Launaeanudicaulis ;Antinociceptive ; anti-inflammatory ; antioxidant activity.

Scavenging Activity, Anti-inflammatory And Diabetes Related Enzyme Inhibition Properties Of Ethanol Leaves Extract Of Phoenyx Dactylifera

Laouini S. E. .  Segni L. .  Gherraf N. .  Ouahrani M. R. .  Mokni S. . 
pages 171-182.


Antinociceptive Activity Of Methanolic Leaf Extract Of Parthenium Hysterophorus L.

Sarwar Shammy .  Shah Marzia Mahjabin Lina .  Md. Shahnewaz Shihab . 
pages 417-427.


Phytochemical Study, Nutritive Value, Antioxidant And Anti-inflammatory Activities Of Phenolic Extracts From Desert Plant Calligonum Comosum L'hér.

صالحة عوادي .  Chouikh Atef .  Chemsa Ahmed Elkhalifa .  Aounallah Chahira .  Aounallah Imane .  Alia Fatma . 
pages 68-75.


Chemical Composition, Acute Toxicity, Antimicrobial And Anti-inflammatory Activities Of Thymus Fontanesii Essential Oil From Algeria

Lamia Sidali Lamia .  Moussa Brada Moussa .  Fauconnier Marie-laure .  Lognay Georges .  Heuskin Stéphanie . 
pages 30-40.